Pharmacokinetic/Pharmacodynamic Target Attainment Based on Measured versus Predicted Unbound Ceftriaxone Concentrations in Critically Ill Patients with Pneumonia: An Observational Cohort Study

The impact of ceftriaxone pharmacokinetic alterations on protein binding and PK/PD target attainment still remains unclear. We evaluated pharmacokinetic/pharmacodynamic (PK/PD) target attainment of unbound ceftriaxone in critically ill patients with severe community-acquired pneumonia (CAP). Besides...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Gijsen, Matthias, Dreesen, Erwin, Van Daele, Ruth, Annaert, Pieter, Debaveye, Yves, Wauters, Joost, Spriet, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151456/
https://ncbi.nlm.nih.gov/pubmed/34064676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10050557
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