Use of Immunodampening To Overcome Diversity in the Malarial Vaccine Candidate Apical Membrane Antigen 1

Apical membrane antigen 1 (AMA1) is a leading malarial vaccine candidate; however, its polymorphic nature may limit its success in the field. This study aimed to circumvent AMA1 diversity by dampening the antibody response to the highly polymorphic loop Id, previously identified as a major target of...

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Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Harris, Karen S., Adda, Christopher G., Khore, Madhavi, Drew, Damien R., Valentini-Gatt, Antonina, Fowkes, Freya J. I., Beeson, James G., Dutta, Sheetij, Anders, Robin F., Foley, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Microbial Immunity and Vaccines
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249334/
https://ncbi.nlm.nih.gov/pubmed/25156737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02061-14
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