Monoclonal Antibodies against Vibrio vulnificus RtxA1 Elicit Protective Immunity through Distinct Mechanisms

Vibrio vulnificus causes rapidly progressing septicemia with an extremely high mortality rate (≥50%), even with aggressive antibiotic treatment. The bacteria secrete multifunctional autoprocessing repeats-in-toxin (MARTX) toxins, which are involved in the pathogenesis of Gram-negative Vibrio species...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Lee, Tae Hee, Cha, Sun-Shin, Lee, Chang-Seop, Rhee, Joon Haeng, Chung, Kyung Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249331/
https://ncbi.nlm.nih.gov/pubmed/25156730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02130-14
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