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A Synthetic Peptide Corresponding to the Extracellular Loop 2 Region of Claudin-4 Protects against Clostridium perfringens Enterotoxin In Vitro and In Vivo

Clostridium perfringens enterotoxin (CPE) action starts when the toxin binds to claudin receptors. Claudins contain two extracellular loop domains, with the second loop (ECL-2) being slightly smaller than the first. CPE has been shown to bind to ECL-2 in receptor claudins. We recently demonstrated t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Shrestha, Archana, Robertson, Susan L., Garcia, Jorge, Beingasser, Juliann, McClane, Bruce A., Uzal, Francisco A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249305/
https://ncbi.nlm.nih.gov/pubmed/25156725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02453-14
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