Human Antibodies to PhtD, PcpA, and Ply Reduce Adherence to Human Lung Epithelial Cells and Murine Nasopharyngeal Colonization by Streptococcus pneumoniae

Streptococcus pneumoniae adherence to human epithelial cells (HECs) is the first step in pathogenesis leading to infections. We sought to determine the role of human antibodies against S. pneumoniae protein vaccine candidates PhtD, PcpA, and Ply in preventing adherence to lung HECs in vitro and mous...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Kaur, Ravinder, Surendran, Naveen, Ochs, Martina, Pichichero, Michael E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249272/
https://ncbi.nlm.nih.gov/pubmed/25245804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02124-14
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