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HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission

The HIV-1 envelope protein (Env) is heavily glycosylated, with approximately 50% of the Env molecular mass being contributed by N-glycans. HIV-1 Env N-glycans shield the protein backbone and have been shown to play key roles in determining Env structure, surface exposure, and, consequently, antigeni...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Shen, Ruizhong, Raska, Milan, Bimczok, Diane, Novak, Jan, Smith, Phillip D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249159/
https://ncbi.nlm.nih.gov/pubmed/25275130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02164-14
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