Modified Vaccinia Virus Ankara Encoding Influenza Virus Hemagglutinin Induces Heterosubtypic Immunity in Macaques

Current influenza virus vaccines primarily aim to induce neutralizing antibodies (NAbs). Modified vaccinia virus Ankara (MVA) is a safe and well-characterized vector for inducing both antibody and cellular immunity. We evaluated the immunogenicity and protective efficacy of MVA encoding influenza vi...

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Udgivet i:J Virol
Main Authors: Florek, Nicholas W., Weinfurter, Jason T., Jegaskanda, Sinthujan, Brewoo, Joseph N., Powell, Tim D., Young, Ginger R., Das, Subash C., Hatta, Masato, Broman, Karl W., Hungnes, Olav, Dudman, Susanne G., Kawaoka, Yoshihiro, Kent, Stephen J., Stinchcomb, Dan T., Osorio, Jorge E., Friedrich, Thomas C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249095/
https://ncbi.nlm.nih.gov/pubmed/25210172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01219-14
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