A modified vaccinia Ankara vaccine vector expressing a mosaic H5 hemagglutinin reduces viral shedding in rhesus macaques

The rapid antigenic evolution of influenza viruses requires frequent vaccine reformulations. Due to the economic burden of continuous vaccine reformulation and the threat of new pandemics, there is intense interest in developing vaccines capable of eliciting broadly cross-reactive immunity to influe...

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Publicat a:PLoS One
Autors principals: Florek, Kelsey R., Kamlangdee, Attapon, Mutschler, James P., Kingstad-Bakke, Brock, Schultz-Darken, Nancy, Broman, Karl W., Osorio, Jorge E., Friedrich, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542451/
https://ncbi.nlm.nih.gov/pubmed/28771513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181738
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