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A Histidine Residue of the Influenza Virus Hemagglutinin Controls the pH Dependence of the Conformational Change Mediating Membrane Fusion
The conformational change of the influenza virus hemagglutinin (HA) protein mediating the fusion between the virus envelope and the endosomal membrane was hypothesized to be induced by protonation of specific histidine residues since their pK(a)s match the pHs of late endosomes (pK(a) of ∼6.0). Howe...
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| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249083/ https://ncbi.nlm.nih.gov/pubmed/25187542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01704-14 |
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