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Adenovirus E1A Targets the DREF Nuclear Factor To Regulate Virus Gene Expression, DNA Replication, and Growth

The adenovirus E1A gene is the first gene expressed upon viral infection. E1A remodels the cellular environment to maximize permissivity for viral replication. E1A is also the major transactivator of viral early gene expression and a coregulator of a large number of cellular genes. E1A carries out i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Radko, Sandi, Koleva, Maria, James, Kris M. D., Jung, Richard, Mymryk, Joe S., Pelka, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249066/
https://ncbi.nlm.nih.gov/pubmed/25210186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02538-14
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