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Effects of Adenovirus Type 5 E1A Isoforms on Viral Replication in Arrested Human Cells

Human adenovirus has evolved to infect and replicate in terminally differentiated human epithelial cells, predominantly those within the airway, the gut, or the eye. To overcome the block to viral DNA replication present in these cells, the virus expresses the Early 1A proteins (E1A). These immediat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Radko, Sandi, Jung, Richard, Olanubi, Oladunni, Pelka, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598095/
https://ncbi.nlm.nih.gov/pubmed/26448631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140124
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