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Effects of Adenovirus Type 5 E1A Isoforms on Viral Replication in Arrested Human Cells

Human adenovirus has evolved to infect and replicate in terminally differentiated human epithelial cells, predominantly those within the airway, the gut, or the eye. To overcome the block to viral DNA replication present in these cells, the virus expresses the Early 1A proteins (E1A). These immediat...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Radko, Sandi, Jung, Richard, Olanubi, Oladunni, Pelka, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598095/
https://ncbi.nlm.nih.gov/pubmed/26448631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140124
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