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Herpes Simplex Virus Internalization into Epithelial Cells Requires Na(+)/H(+) Exchangers and p21-Activated Kinases but neither Clathrin- nor Caveolin-Mediated Endocytosis

Herpes simplex virus 1 (HSV-1) is an alphaherpesvirus that has been reported to infect some epithelial cell types by fusion at the plasma membrane but others by endocytosis. To determine the molecular mechanisms of productive HSV-1 cell entry, we perturbed key endocytosis host factors using specific...

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Publicado en:J Virol
Autores principales: Devadas, Deepika, Koithan, Thalea, Diestel, Randi, Prank, Ute, Sodeik, Beate, Döhner, Katinka
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249063/
https://ncbi.nlm.nih.gov/pubmed/25210183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03631-13
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