The CD8(+) Memory Stem T Cell (T(SCM)) Subset Is Associated with Improved Prognosis in Chronic HIV-1 Infection

Memory stem T cells (T(SCM)) constitute a long-lived, self-renewing lymphocyte population essential for the maintenance of functional immunity. The hallmarks of HIV-1 pathogenesis are CD4(+) T cell depletion and abnormal cellular activation. We investigated the impact of HIV-1 infection on the T(SCM...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Ribeiro, Susan P., Milush, Jeffrey M., Cunha-Neto, Edecio, Kallas, Esper G., Kalil, Jorge, Somsouk, Ma, Hunt, Peter W., Deeks, Steven G., Nixon, Douglas F., SenGupta, Devi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248986/
https://ncbi.nlm.nih.gov/pubmed/25253339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01948-14
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