p16(INK4a) Expression and Immunologic Aging in Chronic HIV Infection

Chronic HIV infection is characterized by increased immune activation and immunosenescence. p16 (INK4a) (p16) is a member of the cyclin-dependent kinase antagonist family that inhibits cellular proliferation, and its protein expression increases during normal chronological aging. However, some infec...

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Pubblicato in:PLoS One
Autori principali: Pereira Ribeiro, Susan, M. Milush, Jeffrey, Cunha-Neto, Edecio, G. Kallas, Esper, Kalil, Jorge, D. Passero, Luiz Felipe, W. Hunt, Peter, G. Deeks, Steven, F. Nixon, Douglas, SenGupta, Devi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115792/
https://ncbi.nlm.nih.gov/pubmed/27861555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166759
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