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Molecular Requirement for Sterols in Herpes Simplex Virus Entry and Infectivity
Herpes simplex virus 1 (HSV-1) required cholesterol or desmosterol for virion-induced membrane fusion. HSV successfully entered DHCR24(−/−) cells, which lack a desmosterol-to-cholesterol conversion enzyme, indicating that entry can occur independently of cholesterol. Depletion of desmosterol from th...
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| 出版年: | J Virol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248969/ https://ncbi.nlm.nih.gov/pubmed/25231306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01615-14 |
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