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Molecular Requirement for Sterols in Herpes Simplex Virus Entry and Infectivity

Herpes simplex virus 1 (HSV-1) required cholesterol or desmosterol for virion-induced membrane fusion. HSV successfully entered DHCR24(−/−) cells, which lack a desmosterol-to-cholesterol conversion enzyme, indicating that entry can occur independently of cholesterol. Depletion of desmosterol from th...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Wudiri, George A., Pritchard, Suzanne M., Li, Hong, Liu, Jin, Aguilar, Hector C., Gilk, Stacey D., Nicola, Anthony V.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248969/
https://ncbi.nlm.nih.gov/pubmed/25231306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01615-14
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