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The Conserved Disulfide Bond within Domain II of Epstein-Barr Virus gH Has Divergent Roles in Membrane Fusion with Epithelial Cells and B Cells

Epstein-Barr virus (EBV) infects target cells via fusion with cellular membranes. For entry into epithelial cells, EBV requires the herpesvirus conserved core fusion machinery, composed of glycoprotein B (gB) and gH/gL. In contrast, for B cell fusion it requires gB and gH/gL with gp42 serving as a c...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Möhl, Britta S., Sathiyamoorthy, Karthik, Jardetzky, Theodore S., Longnecker, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248955/
https://ncbi.nlm.nih.gov/pubmed/25231307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02272-14
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