Residue 82 of the Chikungunya Virus E2 Attachment Protein Modulates Viral Dissemination and Arthritis in Mice

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that has reemerged to cause profound epidemics of fever, rash, and arthralgia throughout sub-Saharan Africa, Southeast Asia, and the Caribbean. Like other arthritogenic alphaviruses, mechanisms of CHIKV pathogenesis are not well defined. Using...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ashbrook, Alison W., Burrack, Kristina S., Silva, Laurie A., Montgomery, Stephanie A., Heise, Mark T., Morrison, Thomas E., Dermody, Terence S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248890/
https://ncbi.nlm.nih.gov/pubmed/25142598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01672-14
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