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Coordinate Regulation of the Suf and Isc Fe-S Cluster Biogenesis Pathways by IscR Is Essential for Viability of Escherichia coli

Fe-S cluster biogenesis is essential for the viability of most organisms. In Escherichia coli, this process requires either the housekeeping Isc or the stress-induced Suf pathway. The global regulator IscR coordinates cluster synthesis by repressing transcription of the isc operon by [2Fe-2S]-IscR a...

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Publicat a:J Bacteriol
Autors principals: Mettert, Erin L., Kiley, Patricia J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248859/
https://ncbi.nlm.nih.gov/pubmed/25266384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01975-14
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