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Regulation of iron-sulfur cluster homeostasis through transcriptional control of the Isc pathway by [2Fe-2S]-IscR in Escherichia coli

Fe-S clusters are essential across the biological world, yet how cells regulate expression of Fe-S cluster biogenesis pathways to cope with changes in Fe-S cluster demand is not well understood. Here, we describe the mechanism by which IscR, a [2Fe-2S] cluster-containing regulator of Escherichia col...

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Detalhes bibliográficos
Main Authors: Giel, Jennifer L., Nesbit, April D., Mettert, Erin L., Fleischhacker, Angela S., Wanta, Brendan T., Kiley, Patricia J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108476/
https://ncbi.nlm.nih.gov/pubmed/23075318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12052
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