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Functional and Structural Analysis of HicA3-HicB3, a Novel Toxin-Antitoxin System of Yersinia pestis

The mechanisms involved in the virulence of Yersinia pestis, the plague pathogen, are not fully understood. In previous research, we found that a Y. pestis mutant lacking the HicB3 (YPO3369) putative orphan antitoxin was attenuated for virulence in a murine model of bubonic plague. Toxin-antitoxin s...

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Библиографические подробности
Опубликовано в: :J Bacteriol
Главные авторы: Bibi-Triki, Sabrina, Li de la Sierra-Gallay, Inès, Lazar, Noureddine, Leroy, Arnaud, Van Tilbeurgh, Herman, Sebbane, Florent, Pradel, Elizabeth
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248797/
https://ncbi.nlm.nih.gov/pubmed/25112480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01932-14
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