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Multiple Low-Dose Challenges in a Rhesus Macaque AIDS Vaccine Trial Result in an Evolving Host Response That Affects Protective Outcome

Using whole-blood transcriptional profiling, we investigated differences in the host response to vaccination and challenge in a rhesus macaque AIDS vaccine trial. Samples were collected from animals prior to and after vaccination with live, irradiated vaccine cells secreting the modified endoplasmic...

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Dades bibliogràfiques
Publicat a:Clin Vaccine Immunol
Autors principals: Selinger, Christian, Strbo, Natasa, Gonzalez, Louis, Aicher, Lauri, Weiss, Jeffrey M., Law, G. Lynn, Palermo, Robert E., Vaccari, Monica, Franchini, Genoveffa, Podack, Eckhard R., Katze, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248781/
https://ncbi.nlm.nih.gov/pubmed/25274805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00455-14
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