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Binding of WIP to Actin Is Essential for T Cell Actin Cytoskeleton Integrity and Tissue Homing
The Wiskott-Aldrich syndrome protein (WASp) is important for actin polymerization in T cells and for their migration. WASp-interacting protein (WIP) binds to and stabilizes WASp and also interacts with actin. Cytoskeletal and functional defects are more severe in WIP(−/−) T cells, which lack WASp, t...
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| Publicado en: | Mol Cell Biol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248745/ https://ncbi.nlm.nih.gov/pubmed/25246631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00533-14 |
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