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Lighter: fast and memory-efficient sequencing error correction without counting

Lighter is a fast, memory-efficient tool for correcting sequencing errors. Lighter avoids counting k-mers. Instead, it uses a pair of Bloom filters, one holding a sample of the input k-mers and the other holding k-mers likely to be correct. As long as the sampling fraction is adjusted in inverse pro...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Song, Li, Florea, Liliana, Langmead, Ben
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248469/
https://ncbi.nlm.nih.gov/pubmed/25398208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0509-9
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