Ventricular assist device implantation improves skeletal muscle function, oxidative capacity, and growth hormone/insulin-like growth factor-1 axis signaling in patients with advanced heart failure

BACKGROUND: Skeletal muscle dysfunction in patients with heart failure (HF) has been linked to impaired growth hormone (GH)/insulin-like growth factor (IGF)-1 signaling. We hypothesized that ventricular assist device (VAD) implantation reverses GH/IGF-1 axis dysfunction and improves muscle metabolis...

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Bibliographic Details
Published in:J Cachexia Sarcopenia Muscle
Main Authors: Khawaja, Tuba, Chokshi, Aalap, Ji, Ruiping, Kato, Tomoko S., Xu, Katherine, Zizola, Cynthia, Wu, Christina, Forman, Daniel E., Ota, Takeyoshi, Kennel, Peter, Takayama, Hiroo, Naka, Yoshifumi, George, Isaac, Mancini, Donna, Schulze, Christian P.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248410/
https://ncbi.nlm.nih.gov/pubmed/25100356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13539-014-0155-9
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