Anamorelin HCl (ONO-7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia-cachexia syndrome: preclinical profile

BACKGROUND: Anamorelin HCl (ANAM) is a novel, orally active, ghrelin receptor agonist in clinical development for the treatment of cancer cachexia. We report in vitro and in vivo studies evaluating the preclinical pharmacologic profile of ANAM. METHODS: Fluorescent imaging plate reader and binding a...

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Detalles Bibliográficos
Publicado en:J Cachexia Sarcopenia Muscle
Main Authors: Pietra, Claudio, Takeda, Yasuhiro, Tazawa-Ogata, Naoko, Minami, Masashi, Yuanfeng, Xia, Duus, Elizabeth Manning, Northrup, Robert
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2014
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248409/
https://ncbi.nlm.nih.gov/pubmed/25267366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13539-014-0159-5
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