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Anamorelin HCl (ONO-7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia-cachexia syndrome: preclinical profile
BACKGROUND: Anamorelin HCl (ANAM) is a novel, orally active, ghrelin receptor agonist in clinical development for the treatment of cancer cachexia. We report in vitro and in vivo studies evaluating the preclinical pharmacologic profile of ANAM. METHODS: Fluorescent imaging plate reader and binding a...
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Publicado no: | J Cachexia Sarcopenia Muscle |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Berlin Heidelberg
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248409/ https://ncbi.nlm.nih.gov/pubmed/25267366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13539-014-0159-5 |
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