Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation

The male-specific lethal dosage compensation complex (MSL-DCC) selectively assembles on the X chromosome in Drosophila males and activates gene transcription by twofold through histone acetylation. An MSL recognition element (MRE) sequence motif nucleates the initial MSL association, but how it is r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Zheng, Sanduo, Villa, Raffaella, Wang, Jia, Feng, Yingang, Wang, Jinfeng, Becker, Peter B., Ye, Keqiong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248295/
https://ncbi.nlm.nih.gov/pubmed/25452275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.250936.114
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