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Solution Structure of MSL2 CXC Domain Reveals an Unusual Zn(3)Cys(9) Cluster and Similarity to Pre-SET Domains of Histone Lysine Methyltransferases

The dosage compensation complex (DCC) binds to single X chromosomes in Drosophila males and increases the transcription level of X-linked genes by approximately twofold. Male-specific lethal 2 (MSL2) together with MSL1 mediates the initial recruitment of the DCC to high-affinity sites in the X chrom...

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Detalhes bibliográficos
Main Authors: Zheng, Sanduo, Wang, Jia, Feng, Yingang, Wang, Jinfeng, Ye, Keqiong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447885/
https://ncbi.nlm.nih.gov/pubmed/23029009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045437
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