Shedding of NG2 by MMP-13 Attenuates Anoikis

Disruption of cell–matrix interactions can lead to anoikis—apoptosis due to loss of matrix contacts. We previously showed that Nerve/glial antigen 2 (NG2) is a novel anoikis receptor. Specifically, overexpression of NG2 leads to anoikis propagation, whereas its suppression leads to anoikis attenuati...

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Udgivet i:DNA Cell Biol
Main Authors: Joo, Nam E., Miao, Di, Bermúdez, Mercedes, Stallcup, William B., Kapila, Yvonne L.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
Fag:
Original Research ArticlesOrganelles/Autophagy/Apoptosis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248241/
https://ncbi.nlm.nih.gov/pubmed/25166220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2014.2399
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