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Targeting the INCENP IN-box–Aurora B interaction to inhibit CPC activity in vivo
The chromosome passenger complex (CPC) is an essential regulator of mitosis and cytokinesis. The CPC consists of Aurora B kinase, inner centromere protein (INCENP), and the targeting subunits survivin and borealin/Dasra B. INCENP is a scaffolding subunit for the CPC and activates Aurora B via its co...
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| Publicat a: | Open Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Royal Society
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248066/ https://ncbi.nlm.nih.gov/pubmed/25392451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.140163 |
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