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Targeting the INCENP IN-box–Aurora B interaction to inhibit CPC activity in vivo
The chromosome passenger complex (CPC) is an essential regulator of mitosis and cytokinesis. The CPC consists of Aurora B kinase, inner centromere protein (INCENP), and the targeting subunits survivin and borealin/Dasra B. INCENP is a scaffolding subunit for the CPC and activates Aurora B via its co...
Gorde:
| Argitaratua izan da: | Open Biol |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Royal Society
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248066/ https://ncbi.nlm.nih.gov/pubmed/25392451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.140163 |
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