A DNA-based molecular probe for optically reporting cellular traction forces

We developed molecular tension probes (TPs) that report traction forces of adherent cells with high spatial resolution, can be linked to virtually any surface, and obviate monitoring deformations of elastic substrates. TPs consist of DNA hairpins conjugated to fluorophore-quencher pairs that unfold...

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Bibliografske podrobnosti
izdano v:Nat Methods
Main Authors: Blakely, Brandon L., Dumelin, Christoph E., Trappmann, Britta, McGregor, Lynn M., Choi, Colin K., Anthony, Peter C., Duesterberg, Van K., Baker, Brendon M., Block, Steven M., Liu, David R., Chen, Christopher S.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247985/
https://ncbi.nlm.nih.gov/pubmed/25306545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3145
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