A DNA-based molecular probe for optically reporting cellular traction forces

We developed molecular tension probes (TPs) that report traction forces of adherent cells with high spatial resolution, can be linked to virtually any surface, and obviate monitoring deformations of elastic substrates. TPs consist of DNA hairpins conjugated to fluorophore-quencher pairs that unfold...

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Publicat a:Nat Methods
Autors principals: Blakely, Brandon L., Dumelin, Christoph E., Trappmann, Britta, McGregor, Lynn M., Choi, Colin K., Anthony, Peter C., Duesterberg, Van K., Baker, Brendon M., Block, Steven M., Liu, David R., Chen, Christopher S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247985/
https://ncbi.nlm.nih.gov/pubmed/25306545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3145
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