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Plasma Gelsolin Levels Decrease in Diabetic State and Increase upon Treatment with F-Actin Depolymerizing Versions of Gelsolin

The study aims to map plasma gelsolin (pGSN) levels in diabetic humans and mice models of type II diabetes and to evaluate the efficacy of gelsolin therapy in improvement of diabetes in mice. We report that pGSN values decrease by a factor of 0.45 to 0.5 in the blood of type II diabetic humans and m...

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Publicat a:J Diabetes Res
Autors principals: Khatri, Neeraj, Sagar, Amin, Peddada, Nagesh, Choudhary, Vikas, Chopra, Bhupinder Singh, Garg, Veena, Garg, Renu, Ashish
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247973/
https://ncbi.nlm.nih.gov/pubmed/25478578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/152075
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