Plasma Gelsolin Levels Decrease in Diabetic State and Increase upon Treatment with F-Actin Depolymerizing Versions of Gelsolin

The study aims to map plasma gelsolin (pGSN) levels in diabetic humans and mice models of type II diabetes and to evaluate the efficacy of gelsolin therapy in improvement of diabetes in mice. We report that pGSN values decrease by a factor of 0.45 to 0.5 in the blood of type II diabetic humans and m...

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Vydáno v:J Diabetes Res
Hlavní autoři: Khatri, Neeraj, Sagar, Amin, Peddada, Nagesh, Choudhary, Vikas, Chopra, Bhupinder Singh, Garg, Veena, Garg, Renu, Ashish
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247973/
https://ncbi.nlm.nih.gov/pubmed/25478578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/152075
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