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Plasma Gelsolin Levels Decrease in Diabetic State and Increase upon Treatment with F-Actin Depolymerizing Versions of Gelsolin

The study aims to map plasma gelsolin (pGSN) levels in diabetic humans and mice models of type II diabetes and to evaluate the efficacy of gelsolin therapy in improvement of diabetes in mice. We report that pGSN values decrease by a factor of 0.45 to 0.5 in the blood of type II diabetic humans and m...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Khatri, Neeraj, Sagar, Amin, Peddada, Nagesh, Choudhary, Vikas, Chopra, Bhupinder Singh, Garg, Veena, Garg, Renu, Ashish
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247973/
https://ncbi.nlm.nih.gov/pubmed/25478578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/152075
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