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Vorinostat synergizes with ridaforolimus and abrogates the ridaforolimus-induced activation of AKT in synovial sarcoma cells

BACKGROUND: Curative treatments for patients with metastatic synovial sarcoma (SS) do not exist, and such patients have a poor prognosis. We explored combinations of molecularly-targeted and cytotoxic agents to identify synergistic treatment combinations in SS cells. METHODS: Two SS cell lines (HS-S...

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Pubblicato in:BMC Res Notes
Autori principali: Morgan, Sherif S, Cranmer, Lee D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247709/
https://ncbi.nlm.nih.gov/pubmed/25406429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-812
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