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MEK1 is associated with carboplatin resistance and is a prognostic biomarker in epithelial ovarian cancer

BACKGROUND: Primary systemic treatment for ovarian cancer is surgery, followed by platinum based chemotherapy. Platinum resistant cancers progress/recur in approximately 25% of cases within six months. We aimed to identify clinically useful biomarkers of platinum resistance. METHODS: A database of o...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Pénzváltó, Zsófia, Lánczky, András, Lénárt, Julianna, Meggyesházi, Nóra, Krenács, Tibor, Szoboszlai, Norbert, Denkert, Carsten, Pete, Imre, Győrffy, Balázs
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247127/
https://ncbi.nlm.nih.gov/pubmed/25408231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-837
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