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A novel c. 204 Ile68Met germline variant in exon 2 of the mutL homolog 1 gene in a colorectal cancer patient

Mutations in the mutL homolog 1 (MLH1) gene are frequent in patients with hereditary non-polyposis colorectal cancer (CRC). The MLH1 gene was screened for mutations in patients with sporadic CRC. The nucleotide sequences for all 19 exons of MLH1 were analyzed by high resolution melting and sequenced...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: VODICKA, PAVEL, CAJA, FABIAN, VYMETALKOVA, VERONIKA, PROCHAZKA, PAVEL, VODICKOVA, LUDMILA, SCHWARZOVA, LUCIE, SLYSKOVA, JANA, KUMAR, RAJIV, SCHNEIDEROVA, MICHAELA
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247117/
https://ncbi.nlm.nih.gov/pubmed/25435955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2666
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