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A novel c. 204 Ile68Met germline variant in exon 2 of the mutL homolog 1 gene in a colorectal cancer patient

Mutations in the mutL homolog 1 (MLH1) gene are frequent in patients with hereditary non-polyposis colorectal cancer (CRC). The MLH1 gene was screened for mutations in patients with sporadic CRC. The nucleotide sequences for all 19 exons of MLH1 were analyzed by high resolution melting and sequenced...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Principais autores: VODICKA, PAVEL, CAJA, FABIAN, VYMETALKOVA, VERONIKA, PROCHAZKA, PAVEL, VODICKOVA, LUDMILA, SCHWARZOVA, LUCIE, SLYSKOVA, JANA, KUMAR, RAJIV, SCHNEIDEROVA, MICHAELA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247117/
https://ncbi.nlm.nih.gov/pubmed/25435955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2666
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