Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation

Mutations in Ras GTPase and various other components of the Ras signaling pathways are among the most common genetic alterations in human cancers and also have been identified in several familial developmental syndromes. Over the past few decades it has become clear that the activity or the oncogeni...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Bunda, Severa, Heir, Pardeep, Srikumar, Tharan, Cook, Jonathan D., Burrell, Kelly, Kano, Yoshihito, Lee, Jeffrey E., Zadeh, Gelareh, Raught, Brian, Ohh, Michael
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246987/
https://ncbi.nlm.nih.gov/pubmed/25157176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406559111
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