Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans

The emergence of pandemic influenza viruses poses a major public health threat. Therefore, there is a need for a vaccine that can induce broadly cross-reactive antibodies that protect against seasonal as well as pandemic influenza strains. Human broadly neutralizing antibodies directed against highl...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ellebedy, Ali H., Krammer, Florian, Li, Gui-Mei, Miller, Matthew S., Chiu, Christopher, Wrammert, Jens, Chang, Cathy Y., Davis, Carl W., McCausland, Megan, Elbein, Rivka, Edupuganti, Srilatha, Spearman, Paul, Andrews, Sarah F., Wilson, Patrick C., García-Sastre, Adolfo, Mulligan, Mark J., Mehta, Aneesh K., Palese, Peter, Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246941/
https://ncbi.nlm.nih.gov/pubmed/25157133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414070111
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