Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

We have previously shown that broadly neutralizing antibodies reactive to the conserved stem region of the influenza virus hemagglutinin (HA) were generated in people infected with the 2009 pandemic H1N1 strain. Such antibodies are rarely seen in humans following infection or vaccination with season...

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Detalhes bibliográficos
Main Authors: Li, Gui-Mei, Chiu, Christopher, Wrammert, Jens, McCausland, Megan, Andrews, Sarah F., Zheng, Nai-Ying, Lee, Jane-Hwei, Huang, Min, Qu, Xinyan, Edupuganti, Srilatha, Mulligan, Mark, Das, Suman R., Yewdell, Jonathan W., Mehta, Aneesh K., Wilson, Patrick C., Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384143/
https://ncbi.nlm.nih.gov/pubmed/22615367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118979109
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