Insulin-like growth factor-I induces epithelial to mesenchymal transition via GSK-3β and ZEB2 in the BGC-823 gastric cancer cell line

Metastasis is the most common cause of mortality in patients with gastric cancer. Epithelial-to-mesenchymal transition (EMT), which may be stimulated by insulin-like growth factor-I (IGF-I) is involved in the metastasis of numerous tumors; however, the molecular mechanism by which IGF-I may induce t...

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Опубликовано в: :Oncol Lett
Главные авторы: LI, HEMING, XU, LING, ZHAO, LEI, MA, YANJU, ZHU, ZHITU, LIU, YUNPENG, QU, XIUJUAN
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2015
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246767/
https://ncbi.nlm.nih.gov/pubmed/25435948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2687
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