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Reactivation of HIC-1 gene by saRNA inhibits clonogenicity and invasiveness in breast cancer cells
Hypermethylated in cancer 1 (HIC-1) is a tumor suppressor gene, which is epigenetically silenced in breast cancer. It is known that the loss of HIC-1, caused by promoter hypermethylation, is associated with tumor aggression and poor survival in breast carcinoma. It has been shown that small activati...
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發表在: | Oncol Lett |
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Main Authors: | , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
D.A. Spandidos
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246611/ https://ncbi.nlm.nih.gov/pubmed/25435951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2633 |
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