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Reactivation of HIC-1 gene by saRNA inhibits clonogenicity and invasiveness in breast cancer cells
Hypermethylated in cancer 1 (HIC-1) is a tumor suppressor gene, which is epigenetically silenced in breast cancer. It is known that the loss of HIC-1, caused by promoter hypermethylation, is associated with tumor aggression and poor survival in breast carcinoma. It has been shown that small activati...
Guardat en:
| Publicat a: | Oncol Lett |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
D.A. Spandidos
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246611/ https://ncbi.nlm.nih.gov/pubmed/25435951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2633 |
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