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Reactivation of HIC-1 gene by saRNA inhibits clonogenicity and invasiveness in breast cancer cells

Hypermethylated in cancer 1 (HIC-1) is a tumor suppressor gene, which is epigenetically silenced in breast cancer. It is known that the loss of HIC-1, caused by promoter hypermethylation, is associated with tumor aggression and poor survival in breast carcinoma. It has been shown that small activati...

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Foilsithe in:Oncol Lett
Main Authors: ZHAO, FENG, PAN, SHENGLI, GU, YAN, GUO, SHANYU, DAI, QIANCHENG, YU, YINGYAN, ZHANG, WEI
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246611/
https://ncbi.nlm.nih.gov/pubmed/25435951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2633
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