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Acute and chronic systemic CB(1) cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats

We investigated acute and chronic effects of CB(1) cannabinoid receptor blockade in renin‐angiotensin system‐dependent hypertension using rimonabant (SR141716A), an orally active antagonist with central and peripheral actions. In transgenic (mRen2)27 rats, a model of angiotensin II‐dependent hyperte...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Schaich, Chris L., Shaltout, Hossam A., Brosnihan, K. Bridget, Howlett, Allyn C., Diz, Debra I.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246581/
https://ncbi.nlm.nih.gov/pubmed/25168868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12108
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