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A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case–control study
BACKGROUND: One of the hallmarks of cancer is the occurrence of high levels of chromosomal rearrangements as a result of inaccurate repair of double-strand breaks (DSB). Germline mutations in BRCA and RAD51 genes, involved in DSB repair, are strongly associated with hereditary breast cancer. Pol θ,...
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| 出版年: | BMC Cancer |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246548/ https://ncbi.nlm.nih.gov/pubmed/25409685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-850 |
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