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Simple HPLC-UV method for the quantification of metformin in human plasma with one step protein precipitation

This study presents the optimization of a simple HPLC-UV method for the determination of metformin in human plasma. Ion pair separation followed by UV detection was performed on deproteinized human plasma samples. The separation was carried out on a Discovery Reversed Phase C-18 column (250 × 4.6 mm...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Chhetri, Himal Paudel, Thapa, Panna, Van Schepdael, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246406/
https://ncbi.nlm.nih.gov/pubmed/25473337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2013.12.011
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