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Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation
We have developed a screening platform for the isolation of genetic entities involved in metastatic reactivation. Retroviral libraries of cDNAs from fully metastatic breast-cancer cells or pooled microRNAs were transduced into breast-cancer cells that become dormant upon infiltrating the lung. Upon...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246349/ https://ncbi.nlm.nih.gov/pubmed/25378704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403234111 |
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