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Halorhodopsin pumps Cl(–) and bacteriorhodopsin pumps protons by a common mechanism that uses conserved electrostatic interactions
Key mutations differentiate the functions of homologous proteins. One example compares the inward ion pump halorhodopsin (HR) and the outward proton pump bacteriorhodopsin (BR). Of the nine essential buried ionizable residues in BR, six are conserved in HR. However, HR changes three BR acids, D85 in...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246344/ https://ncbi.nlm.nih.gov/pubmed/25362051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411119111 |
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