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Microtubules stabilize cell polarity by localizing rear signals
Microtubules are known to play an important role in cell polarity; however, the mechanism remains unclear. Using cells migrating persistently on micropatterned strips, we found that depolymerization of microtubules caused cells to change from persistent to oscillatory migration. Mathematical modelin...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246331/ https://ncbi.nlm.nih.gov/pubmed/25368191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410533111 |
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